Article
Whole genome prediction and heritability of childhood asthma phenotypes.
Immunity, inflammation and disease - 1 Dec 2016
McGeachie Michael J, Clemmer George L, Croteau-Chonka Damien C, Castaldi Peter J, Cho Michael H, Sordillo Joanne E, Lasky-Su Jessica A, Raby Benjamin A, Tantisira Kelan G, Weiss Scott T
Abstract excerpt
INTRODUCTION: While whole genome prediction (WGP) methods have recently demonstrated successes in the prediction of complex genetic diseases, they have not yet been applied to asthma and related phenotypes. Longitudinal patterns of lung function differ between asthmatics, but these phenotypes have not been assessed for heritability or predictive ability. Herein, we assess the heritability and genetic...
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