Article

Polygenic risk scores associate with asthma phenotypes and proteomic analyses implicate IL1R1 in two family-based studies

2026-06-11

Abstract excerpt

Despite its high prevalence and the discovery of hundreds of genetic associations, the genetic determinants and heterogeneous manifestations of asthma remain incompletely understood. Incorporating polygenic risk scores (PRS) into asthma research offers a powerful approach to quantify inherited susceptibility, refine risk profiles, and advance mechanistic understanding of disease development. For this study, we lev...

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Literature Corpus work: 1f0967eb-fa16-5701-a867-1890713f5ff2
DOI: 10.64898/2026.06.06.26355045

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