Article

Cumulative Genetic Risk for Asthma Contributes to Disease Severity in Children with Asthma

2025-09-09

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Childhood-onset asthma is highly heritable, with nearly 200 risk loci identified in genome-wide association studies. Aggregated polygenic risk scores can be used to quantify genetic predisposition to asthma, but their power to predict asthma severity in multi-ancestral groups has not been previously evaluated. <h4>Objective</h4> Our aim was to examine the predictive power o...

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Literature Corpus work: 1457f935-684f-5b70-98da-0d4a462c43df
DOI: 10.1101/2025.09.08.25335346

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