Article

Multimodal gene prioritization reveals nonlinear regulatory architecture in childhood-onset asthma

2026-07-16

Abstract excerpt

<h4>Summary</h4> Asthma is a heritable complex disease that disproportionately burdens minority and admixed populations in the US. However, the causal genes and regulatory mechanisms governing inherited risk remain largely unresolved. We performed a European-ancestry meta-analysis of 141,894 cases and 1,361,846 controls drawn from the Trans-national Asthma Genetic Consortium (TAGC) and Global Biobank Meta-analysi...

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Literature Corpus work: 1175de08-102f-57d6-8a75-2467185a3f04
DOI: 10.64898/2026.07.14.26357983

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