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Article

A previously unreported impact of a PLA2G7 gene polymorphism on the plasma levels of lipoprotein-associated phospholipase A2 activity and mass.

Scientific reports - 1 Dec 2016

Qi Yue, Zhao Dong, Jia Zhangrong, Wang Wei, Wang Miao, Sun Jiayi, Liu Jun, Li Yan, Xie Wuxiang, Liu Jing

Abstract excerpt

Lipoprotein-associated phospholipase A2 (Lp-PLA2) levels are associated with the development of atherosclerosis. We aimed to assess the genetic determinants of Lp-PLA2 activity and mass by genotyping multiple polymorphisms in PLA2G7, the gene encoding Lp-PLA2, among 1258 participants from the Chinese Multi-provincial Cohort Study-Beijing Project. The Sequenom MassARRAY system, Taqman assay and direct sequencing...

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Identifiers

PMID: 27905470
DOI: 10.1038/srep37465
PMCID: PMC5131362

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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