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Article

Effects of V279F in the Lp-PLA(2) gene on markers of oxidative stress and inflammation in Koreans.

Clinica chimica acta; international journal of clinical chemistry - 2 Apr 2010

Paik Jean Kyung, Chae Jey Sook, Jang Yangsoo, Kim Ji Young, Kim Oh Yoen, Jeong Tae-Sook, Lee Sang-Hyun, Lee Jong Ho

Abstract excerpt

BACKGROUND: A single nucleotide polymorphism (SNP), V279F, in the lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) gene is known to influence enzyme activity. It is unclear whether Lp-PLA(2) exerts pro- or antiatherogenic effects in humans. We investigated the interplay between V279F, Lp-PLA(2) activity, oxidative stress and inflammation. METHODS: We genotyped 2914 healthy Koreans (43-79years) for the...

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PMID: 20080080
DOI: 10.1016/j.cca.2009.12.021

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PGF
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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