Article
Associations of PLA2G7 gene polymorphisms with plasma lipoprotein-associated phospholipase A2 activity and coronary heart disease in a Chinese Han population: the Beijing atherosclerosis study.
Human genetics - 1 Feb 2009
Hou Liping, Chen Shufeng, Yu Hongjiang, Lu Xiangfeng, Chen Jianhong, Wang Laiyuan, Huang Jianfeng, Fan Zhongjie, Gu Dongfeng
Abstract excerpt
The human PLA2G7 gene encodes lipoprotein-associated phospholipase A(2) (Lp-PLA(2)), an emerging risk factor for cardiovascular diseases. In the present study, seven single nucleotide polymorphisms (SNPs) in the PLA2G7 gene were genotyped in 827 patients with coronary heart disease (CHD), of which 512 were patients with myocardial infarction (MI), and 947 age- and gender-matched controls in a Chinese Han...
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