Article
Interaction between nonsynonymous polymorphisms in PLA2G7 gene and smoking on the risk of coronary heart disease in a Chinese population.
Journal of thrombosis and thrombolysis - 1 Jul 2018
Chi Yunpeng, Shi Conghong, Zhang Xiaojiang, Xi Yang
Abstract excerpt
To investigate the impact of PLA2G7 polymorphism, and additional their interactions with smoking and drinking on coronary heart disease (CHD) risk based on Chinese population. GMDR model was used to screen the best gene-smoking and gene-drinking interaction combinations. Logistic regression was performed to investigate association between 4 SNPs and CHD, and the interaction effect between rs1805017 and smoking....
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