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Article

Drosophila WASH is required for integrin-mediated cell adhesion, cell motility and lysosomal neutralization.

Journal of cell science - 15 Jan 2017

Nagel Benedikt M, Bechtold Meike, Rodriguez Luis Garcia, Bogdan Sven

Abstract excerpt

The Wiskott-Aldrich syndrome protein and SCAR homolog (WASH; also known as Washout in flies) is a conserved actin-nucleation-promoting factor controlling Arp2/3 complex activity in endosomal sorting and recycling. Previous studies have identified WASH as an essential regulator in Drosophila development. Here, we show that homozygous wash mutant flies are viable and fertile. We demonstrate that Drosophila WASH has...

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Identifiers

PMID: 27884932
DOI: 10.1242/jcs.193086

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Drosophila WASH is required for integrin-mediated cell adhesion, cell motility and lysosomal neutralization.PMID 27884932Read ↗

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