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Article

Wash exhibits context-dependent phenotypes and, along with the WASH regulatory complex, regulates Drosophila oogenesis.

Journal of cell science - 13 Apr 2018

Verboon Jeffrey M, Decker Jacob R, Nakamura Mitsutoshi, Parkhurst Susan M

Abstract excerpt

WASH, a Wiskott-Aldrich syndrome (WAS) family protein, has many cell and developmental roles related to its function as a branched actin nucleation factor. Similar to mammalian WASHC1, which is embryonic lethal, Drosophila Wash was found to be essential for oogenesis and larval development. Recently, however, Drosophila wash was reported to be homozygous viable. Here, we verify that the original wash null allele...

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Identifiers

PMID: 29549166
DOI: 10.1242/jcs.211573
PMCID: PMC5963843

Genes

WASHC1

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Wash exhibits context-dependent phenotypes and, along with the WASH regulatory complex, regulates Drosophila oogenesis.PMID 29549166Read ↗

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