Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Wash interacts with lamin and affects global nuclear organization.

Current biology : CB - 16 Mar 2015

Verboon Jeffrey M, Rincon-Arano Hector, Werwie Timothy R, Delrow Jeffrey J, Scalzo David, Nandakumar Vivek, Groudine Mark, Parkhurst Susan M

Abstract excerpt

The cytoplasmic functions of Wiskott-Aldrich syndrome family (WAS) proteins are well established and include roles in cytoskeleton reorganization and membrane-cytoskeletal interactions important for membrane/vesicle trafficking, morphogenesis, immune response, and signal transduction. Misregulation of these proteins is associated with immune deficiency and metastasis [1-4]. Cytoplasmic WAS proteins act as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Cell Nucleus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila Proteins

Share to Gene Knockdown Techniques

Share to Genes, Insect

Share to Heterochromatin

Share to Lamins

Share to Vesicular Transport Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 25754639
DOI: 10.1016/j.cub.2015.01.052
PMCID: PMC4366290

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Wash interacts with lamin and affects global nuclear organization.PMID 25754639Read ↗

Developmental expression of <i>Drosophila</i> Wiskott‐Aldrich Syndrome family proteinsSemantic proximity Read ↗

Wash and the WASH Regulatory Complex function in Nuclear Envelope buddingSemantic proximity Read ↗

Wash exhibits context-dependent phenotypes and, along with the WASH regulatory complex, regulates Drosophila oogenesis.Semantic proximity Read ↗

Cellular functions of WASP family proteins at a glanceSemantic proximity Read ↗

WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc–dependent mannerSemantic proximity Read ↗

Drosophila WASH is required for integrin-mediated cell adhesion, cell motility and lysosomal neutralization.Semantic proximity Read ↗

Wash functions downstream of Rho and links linear and branched actin nucleation factorsSemantic proximity Read ↗

Human subtelomeric WASH genes encode a new subclass of the WASP family.Semantic proximity Read ↗

WASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes.Semantic proximity Read ↗

Networking in the nucleus: a spotlight on LEM-domain proteins.Semantic proximity Read ↗

Tissue-specific defects are caused by loss of the Drosophila MAN1 LEM domain protein.Semantic proximity Read ↗

All in the family: evidence for four new LEM-domain proteins Lem2 (NET-25), Lem3, Lem4 and Lem5 in the human genome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.