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DNA methylation and cancer development: molecular mechanism.

Cell biochemistry and biophysics - 1 Nov 2013

Akhavan-Niaki Haleh, Samadani Ali Akbar

Abstract excerpt

DNA methylation is a significant regulator of gene expression, and its role in carcinogenesis recently has been a subject of remarkable interest. The aim of this review is to analyze the mechanism and cell regulatory effects of both hypo- and hyper-DNA methylation on cancer. In this review, we report new developments and their implications regarding the effects of DNA methylation on cancer development. Indeed,...

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PMID: 23508887
DOI: 10.1007/s12013-013-9555-2

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Source receipt: pubmed, retrieved 7 Sept 2026.

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