Article
Genome-Wide Analysis of DNA Methylation Dynamics during Early Human Development
11 Dec 2014
Abstract excerpt
DNA methylation is globally reprogrammed during mammalian preimplantation development, which is critical for normal development. Recent reduced representation bisulfite sequencing (RRBS) studies suggest that the methylome dynamics are essentially conserved between human and mouse early embryos. RRBS is known to cover 5-10% of all genomic CpGs, favoring those contained within CpG-rich regions. To obtain an...
Topics
Join the communities discussing this publication.