Article
DNA methylation in mammalian development and disease.
Birth defects research. Part C, Embryo today : reviews - 1 Jun 2005
Dean Wendy, Lucifero Diana, Santos Fátima
Abstract excerpt
Epigenetic modification of the cytosine base of DNA by its methylation introduced the possibility that beyond the inherent information contained within the nucleotide sequence there was an additional layer of information added to the underlying genetic code. DNA methylation has been implicated in a wide range of biological functions, including an essential developmental role in the reprogramming of germ cells and...
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