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Article

DNA methylation: an introduction to the biology and the disease-associated changes of a promising biomarker.

Molecular biotechnology - 1 Jan 2010

Tost Jörg

Abstract excerpt

DNA methylation occurring on the 5 position of the pyrimidine ring of cytosines in the context of the dinucleotide sequence CpG forms one of the multiple layers of epigenetic mechanisms controlling and modulating gene expression through chromatin structure. It closely interacts with histone modifications and chromatin remodeling complexes to form the genomic chromatin landscape. DNA methylation is essential for...

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PMID: 19842073
DOI: 10.1007/s12033-009-9216-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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