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Article

Differential Effects of APOE Genotypes on the Anterior and Posterior Subnetworks of Default Mode Network in Amnestic Mild Cognitive Impairment.

Journal of Alzheimer's disease : JAD - 18 Oct 2016

Yuan Baoyu, Xie Chunming, Shu Hao, Liao Wenxiang, Wang Zan, Liu Duan, Zhang Zhijun

Abstract excerpt

BACKGROUND: The apolipoprotein E (APOE) ɛ4 carriers are at increased risk of developing Alzheimer's disease (AD) while the ɛ2 carriers appear to be protected against the disease. The default mode network (DMN), based in ventromedial prefrontal cortex (vmPFC) and posterior cingulate cortex (PCC), consists of functionally differentiable anterior and posterior subnetworks. OBJECTIVE: This study was to investigate...

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Source

Identifiers

PMID: 27589521
DOI: 10.3233/JAD-160353

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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