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APOE ε4-related structural vulnerability in mild cognitive impairment: a subsystem-based analysis of the default mode network

2026-05-11

Abstract excerpt

<title>Abstract</title> <p> Background Mild cognitive impairment (MCI) is a critical prodromal stage of progressive cognitive decline. As a core cognitive brain network, the default mode network (DMN) exhibits structural alterations in MCI that are closely associated with cognitive impairment. <italic>Apolipoprotein E ε4 (APOE ε4)</italic> , the strongest genetic risk factor for pathological cognitive decline...

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Literature Corpus work
8c26ff4a-ca14-59d0-96df-65e57b33c548
DOI
10.21203/rs.3.rs-9447482/v1
Open publication

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APOE ε4-related structural vulnerability in mild cognitive impairment: a subsystem-based analysis of the default mode networkDOI 10.21203/rs.3.rs-9447482/v1
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