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APOE Polymorphism Affects Brain Default Mode Network in Healthy Young Adults

1 Dec 2015

Abstract excerpt

To investigate the effect of apolipoprotein E (APOE) gene polymorphism on the resting-state brain function, structure, and blood flow in healthy adults younger than 35 years, using multimodality magnetic resonance (MR) imaging.Seventy-six healthy adults (34 men, 23.7 ± 2.8 y; 31 APOE ε4/ε3 carriers, 31 ε3/ε3 carriers, and 14 ε2/ε3 carriers) were included. For resting-state functional MRI data, default mode...

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PMID: 26717353
DOI: 10.1097/md.0000000000001734

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