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Article

Recognition memory is associated with altered resting-state functional connectivity in people at genetic risk for Alzheimer's disease.

The European journal of neuroscience - 1 Oct 2014

Matura Silke, Prvulovic David, Butz Marius, Hartmann Daniel, Sepanski Beate, Linnemann Katja, Oertel-Knöchel Viola, Karakaya Tarik, Fußer Fabian, Pantel Johannes, van de Ven Vincent

Abstract excerpt

The apolipoprotein E ε4 (ApoE ε4) allele not only represents the strongest single genetic risk factor for sporadic Alzheimer's disease, but also imposes independent effects on brain function in healthy individuals where it has been shown to promote subtle memory deficits and altered intrinsic functional brain network connectivity. Based on previous work showing a potential relevance of the default mode network...

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Identifiers

PMID: 24989884
DOI: 10.1111/ejn.12659

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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