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Article

Direct interrogation of the role of H3K9 in metazoan heterochromatin function.

Genes & development - 15 Aug 2016

Penke Taylor J R, McKay Daniel J, Strahl Brian D, Matera A Gregory, Duronio Robert J

Abstract excerpt

A defining feature of heterochromatin is methylation of Lys9 of histone H3 (H3K9me), a binding site for heterochromatin protein 1 (HP1). Although H3K9 methyltransferases and HP1 are necessary for proper heterochromatin structure, the specific contribution of H3K9 to heterochromatin function and animal development is unknown. Using our recently developed platform to engineer histone genes in Drosophila, we...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27566777
DOI: 10.1101/gad.286278.116
PMCID: PMC5024684

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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