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Article

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.

Nature - 1 Mar 2001

Lachner M, O'Carroll D, Rea S, Mechtler K, Jenuwein T

Abstract excerpt

Distinct modifications of histone amino termini, such as acetylation, phosphorylation and methylation, have been proposed to underlie a chromatin-based regulatory mechanism that modulates the accessibility of genetic information. In addition to histone modifications that facilitate gene activity, it is of similar importance to restrict inappropriate gene expression if cellular and developmental programmes are to...

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PMID: 11242053
DOI: 10.1038/35065132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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