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Article

Multiple SET methyltransferases are required to maintain normal heterochromatin domains in the genome of Drosophila melanogaster.

Genetics - 1 Apr 2009

Brower-Toland Brent, Riddle Nicole C, Jiang Hongmei, Huisinga Kathryn L, Elgin Sarah C R

Abstract excerpt

Methylation of histone H3 lysine 9 (H3K9) is a key feature of silent chromatin and plays an important role in stabilizing the interaction of heterochromatin protein 1 (HP1) with chromatin. Genomes of metazoans such as the fruit fly Drosophila melanogaster generally encode three types of H3K9-specific SET domain methyltransferases that contribute to chromatin homeostasis during the life cycle of the organism....

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Share to Animals, Genetically Modified
Share to Chromatin Assembly and Disassembly

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Genome, Insect

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Share to Histone-Lysine N-Methyltransferase

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Source

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Identifiers

PMID: 19189944
DOI: 10.1534/genetics.108.100271
PMCID: PMC2666501

Genes

SET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Multiple SET methyltransferases are required to maintain normal heterochromatin domains in the genome of Drosophila melanogaster.PMID 19189944Read ↗

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