Article
A heterochromatic histone methyltransferase lowers nucleosome occupancy at euchromatic promoters
2018-09-27
Abstract excerpt
H3K9me3 (histone H3 modified with tri-methylation at lysine 9) is a hallmark of transcriptional silencing and heterochromatin. However, its global effects on the genome, including euchromatin, are less well understood. Here we develop Formaldehyde-Assisted Identification of Regulatory Elements (FAIRE) for C. elegans to examine the chromatin configuration of mutants that lack virtually all H3K9me3, while leaving H...
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Identifiers and source
- Literature Corpus work
- 876720f5-3412-52af-99ff-5a127c0dd206
- DOI
- 10.1101/429191