Article
Functional Redundancy of Variant and Canonical Histone H3 Lysine 9 Modification in Drosophila.
Genetics - 1 Jan 2018
Penke Taylor J R, McKay Daniel J, Strahl Brian D, Matera A Gregory, Duronio Robert J
Abstract excerpt
Histone post-translational modifications (PTMs) and differential incorporation of variant and canonical histones into chromatin are central modes of epigenetic regulation. Despite similar protein sequences, histone variants are enriched for different suites of PTMs compared to their canonical counterparts. For example, variant histone H3.3 occurs primarily in transcribed regions and is enriched for "active"...
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