Article
cis-Acting determinants of heterochromatin formation on Drosophila melanogaster chromosome four.
Molecular and cellular biology - 1 Sept 2004
Sun Fang-Lin, Haynes Karmella, Simpson Cory L, Lee Susan D, Collins Lynne, Wuller Jo, Eissenberg Joel C, Elgin S C R
Abstract excerpt
The heterochromatic domains of Drosophila melanogaster (pericentric heterochromatin, telomeres, and the fourth chromosome) are characterized by histone hypoacetylation, high levels of histone H3 methylated on lysine 9 (H3-mK9), and association with heterochromatin protein 1 (HP1). While the specific interaction of HP1 with both H3-mK9 and histone methyltransferases suggests a mechanism for the maintenance of...
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