Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aurora A is a prognostic marker for breast cancer arising in BRCA2 mutation carriers

30 Sept 2014

Abstract excerpt

Overexpression of the Aurora A kinase has been shown to have prognostic value in breast cancer. Previously, we showed a significant association between AURKA gene amplification and BRCA2 mutation in breast cancer. The aim of this study was to assess the prognostic impact of Aurora A overexpression on breast cancer arising in BRCA2 mutation carriers. Aurora A expression was evaluated by immunohistochemistry on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to DNA Repair Mechanisms
Share to Microtubule and mitosis dynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27499891
DOI: 10.1002/cjp2.6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aurora A is a prognostic marker for breast cancer arising in BRCA2 mutation carriersPMID 27499891Read ↗

Aurora-A amplification associated with BRCA2 mutation in breast tumours.Semantic proximity Read ↗

A comprehensive analysis of Aurora A; transcript levels are the most reliable in association with proliferation and prognosis in breast cancerSemantic proximity Read ↗

Aurora-A gene is frequently amplified in basal-like breast cancer.Semantic proximity Read ↗

Aurora kinases A and B and familial breast cancer risk.Semantic proximity Read ↗

Gene Amplification and Overexpression of Aurora-C in Breast and Prostate Cancer Cell LinesSemantic proximity Read ↗

Sensitivity of BRCA2 mutated human cell lines to Aurora kinase inhibition.Semantic proximity Read ↗

AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 study.Semantic proximity Read ↗

Aurora A is a negative prognostic factor and a new therapeutic target in human neuroblastomaSemantic proximity Read ↗

Her-2/neu gene amplification in familial vs sporadic breast cancer. Impact on the behavior of the disease.Semantic proximity Read ↗

Pharmacogenetic profiling of Aurora kinase B is associated with overall survival in metastatic colorectal cancer.Semantic proximity Read ↗

Functional Phe31Ile polymorphism in Aurora A and risk of breast carcinoma.Semantic proximity Read ↗

PHLDA1 is a crucial negative regulator and effector of Aurora A kinase in breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.