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Article

Aurora kinases A and B and familial breast cancer risk.

Cancer letters - 18 Mar 2007

Tchatchou Sandrine, Wirtenberger Michael, Hemminki Kari, Sutter Christian, Meindl Alfons, Wappenschmidt Barbara, Kiechle Marion, Bugert Peter, Schmutzler Rita K, Bartram Claus R, Burwinkel Barbara

Abstract excerpt

Aurora genes play a crucial role in tumourigenesis and are overexpressed in many kinds of cancers. We investigated whether coding variants within the Aurora genes are associated with familial breast cancer risk. While AURKA Phe31Ile (1712T>A) and AURKB Thr298Met (893G>A) showed no association, the synonymous AURKB Ser295Ser (885A>G) polymorphism resulted in an increased breast cancer risk for carriers of the...

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Identifiers

PMID: 16762494
DOI: 10.1016/j.canlet.2006.05.002

Genes

AURKB
AURKA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Aurora kinases A and B and familial breast cancer risk.PMID 16762494Read ↗

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The AURKA gene rs2273535 polymorphism contributes to breast carcinoma risk - meta-analysis of eleven studies.Semantic proximity Read ↗

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