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Article

Aurora-A gene is frequently amplified in basal-like breast cancer.

Oncology reports - 1 Feb 2010

Staff Synnöve, Isola Jorma, Jumppanen Mervi, Tanner Minna

Abstract excerpt

Aurora-A is a serine-threonine kinase having vital cellular functions in mitosis and is a promising target for therapy in treating patients with cancer. This study assesses the clinicopathological associations of AURKA gene amplification in clinical breast tumors and association of gene copy number with its mRNA and protein expression in breast cancer cell lines. In this pilot study, we examined Aurora-A gene...

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Source

Identifiers

PMID: 20043089

Genes

AURKA
CISH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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