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Article

Her-2/neu gene amplification in familial vs sporadic breast cancer. Impact on the behavior of the disease.

American journal of clinical pathology - 1 Dec 2003

Espinosa Ana B, Tabernero Maria D, García-Macías Maria C, Primo Daniel, Bernal Amalia Gómez, Cruz Juan J, Ramos Manuel, Font de Mora Jaime, Gómez Alonso Alberto, Orfao Alberto

Abstract excerpt

We compared the incidence of Her-2/neu amplification in patients with and without a family history of breast cancer and correlated gene status with clinicobiologic and prognostic features in sporadic and familial cases. Of 108 patients, 28.7% had gene amplification. Among 96 cases with family his...

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Identifiers

PMID: 14671981
DOI: 10.1309/5H77-8W5K-75CM-M03W

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14671981-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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