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Article

Development of renal atrophy in murine 2 kidney 1 clip hypertension is strain independent.

Research in veterinary science - 1 Aug 2016

Kashyap Sonu, Boyilla Rajendra, Zaia Paula J, Ghossan Roba, Nath Karl A, Textor Stephen C, Lerman Lilach O, Grande Joseph P

Abstract excerpt

The murine 2-kidney 1-clip (2K1C) model has been used to identify mechanisms underlying chronic renal disease in human renovascular hypertension. Although this model recapitulates many of the features of human renovascular disease, strain specific variability in renal outcomes and animal-to-animal variation in the degree of arterial stenosis are well recognized limitations. In particular, the C57BL/6J strain is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27473991
DOI: 10.1016/j.rvsc.2016.06.002
PMCID: PMC4967495

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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