Article

Strain Matters: The 129S1/SvlmJ Mouse Model Reveals the Genetic and Inflammatory Susceptibility to Hypertensive Complications

2025-03-26

Abstract excerpt

<h4>Background</h4> Hypertension is a leading cause of microvascular injury, yet the genetic determinants of organ-specific vulnerability remain poorly understood. Yest, we need good mouse models to investigate the complication of hypertension. This study investigates the role of genetic background in shaping hypertensive complications by comparing two mouse strains with divergent inflammatory responses. <h4>Meth...

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Literature Corpus work: 72398cd1-062f-5ce9-9259-2b9aaf850801
DOI: 10.1101/2025.03.24.641145

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