Back to search

Article

Cardiovascular manifestations of renovascular hypertension in diabetic mice

2015-12-03

Abstract excerpt

<h4>Purpose: </h4> Type 2 diabetes is the leading cause of end stage renal disease in the United States. Atherosclerotic renal artery stenosis is commonly observed in diabetic patients and impacts the rate of renal and cardiovascular disease progression. We hypothesized that renal artery stenosis contributes to bilateral renal disease in diabetics. In our original study, we found that leptin-deficient diabetic (db...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
f7cc365d-befa-593e-bd25-53b2ca22332b
DOI
10.7287/peerj.preprints.1323v2
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Cardiovascular manifestations of renovascular hypertension in diabetic miceDOI 10.7287/peerj.preprints.1323v2
Cardiovascular phenotype in Smad3 deficient mice with renovascular hypertension.Semantic proximity
A murine model of cardiovascular-kidney-metabolic syndrome demonstrates compromised limb function in the ischemic hind limbSemantic proximity
Model-Dependent Renal Phenotypes in Diabetic Kidney Disease: Comparative Histopathological Characterization of Commonly Used Animal ModelsSemantic proximity
Mouse models of diabetic nephropathy.Semantic proximity
Renal Fibrosis Is Significantly Attenuated Following Targeted Disruption of Cd40 in Experimental Renal Ischemia.Semantic proximity
Development of renal atrophy in murine 2 kidney 1 clip hypertension is strain independent.Semantic proximity
Genetic deficiency of Smad3 protects the kidneys from atrophy and interstitial fibrosis in 2K1C hypertension.Semantic proximity
Ultrasonographic Characterization of the db/db Mouse: An Animal Model of Metabolic Abnormalities.Semantic proximity
Advances in Murine Models of Diabetic NephropathySemantic proximity
Diabetic eNOS knockout mice develop distinct macro- and microvascular complications.Semantic proximity
Loss of endothelial glucocorticoid receptor accelerates organ fibrosis in <i>db/db</i> miceSemantic proximity
A novel mouse model of hypertensive emergency with multiorgan microvascular disease implicating the VEGFA/sFlt-1 balanceSemantic proximity
Select a neighboring publication to make it the new centre.