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Article

Differential Expression of Hypertensive Phenotypes in BXD Mouse Strains in Response to Angiotensin II.

American journal of hypertension - 8 Dec 2017

Zhao Wenyuan, Zhao Tieqiang, Chen Yuanjian, Bhattacharya Syamal K, Lu Lu, Sun Yao

Abstract excerpt

BACKGROUND: Besides environmental risk factors, genetic factors play a crucial role in the pathogenesis of primary hypertension. The current study is to unravel whether hypertensive phenotypes vary in mice with different genetic background. METHODS: Hypertension was induced in C57BL/6J (B6), DBA/2J (D2), and 25 BXD strains by administrating angiotensin (Ang)II (2.5 mg/kg/day infused by osmotic minipump) for 4...

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Identifiers

PMID: 29036574
DOI: 10.1093/ajh/hpx144
PMCID: PMC5861568

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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