Article
Non-Transgenic Mouse Models of Kidney Disease.
Nephron - 1 Jan 2016
Rabe Michael, Schaefer Franz
Abstract excerpt
Animal models are essential tools to understand the mechanisms underlying the development and progression of renal disease and to study potential therapeutic approaches. Recently, interventional models suitable to induce acute and chronic kidney disease in the mouse have become a focus of interest due to the wide availability of genetically engineered mouse lines. These models differ by their damaging mechanism...
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