Animal models of hypertension: an overview.

doi:10.1016/j.lab.2005.05.005

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Article

Animal models of hypertension: an overview.

The Journal of laboratory and clinical medicine - 1 Sept 2005

Lerman Lilach O, Chade Alejandro R, Sica Vincenzo, Napoli Claudio

Abstract excerpt

Hypertension is a multifactorial disease involving complex interactions between genetic and environmental factors. Development of experimental models of hypertension allowed dissection and isolation of various factors associated with regulation of blood pressure, inheritance of hypertensive traits, and cellular responses to injury. The phenotype-driven approach is taking advantage of selective breeding of animals...

Topics

Animals
Disease Models, Animal
Dogs
Gene Expression
Genotype
Hypertension
Phenotype
Rabbits
Rats
Swine

Source

Open in PubMed

Identifiers

PMID: 16131455
DOI: 10.1016/j.lab.2005.05.005

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