Article
Animal models of hypertension: an overview.
The Journal of laboratory and clinical medicine - 1 Sept 2005
Lerman Lilach O, Chade Alejandro R, Sica Vincenzo, Napoli Claudio
Abstract excerpt
Hypertension is a multifactorial disease involving complex interactions between genetic and environmental factors. Development of experimental models of hypertension allowed dissection and isolation of various factors associated with regulation of blood pressure, inheritance of hypertensive traits, and cellular responses to injury. The phenotype-driven approach is taking advantage of selective breeding of animals...
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