Article
Impact of SORL1 genetic variations on MRI markers in non-demented elders.
Oncotarget - 31 May 2016
Yin Rui-Hua, Li Jun, Tan Lin, Wang Hui-Fu, Tan Meng-Shan, Yu Wan-Jiang, Tan Chen-Chen, Yu Jin-Tai, Tan Lan
Abstract excerpt
The sorting protein-related receptor 1 (SORL1 or LR11) gene has been verified to play an important role in the pathologic process of β-amyloid (Aβ) formation and trafficking in Alzheimer's Disease (AD) by plenty of cytological and molecular biological studies. But there were few studies investigated the association of SORL1 gene and neurodegeneration features from a rather macroscopic perspective. In the present...
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