SORL1 variants and risk of late-onset Alzheimer's disease.

doi:10.1016/j.nbd.2007.09.001

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Article

SORL1 variants and risk of late-onset Alzheimer's disease.

Neurobiology of disease - 1 Feb 2008

Li Yonghong, Rowland Charles, Catanese Joseph, Morris John, Lovestone Simon, O'Donovan Michael C, Goate Alison, Owen Michael, Williams Julie, Grupe Andrew

Abstract excerpt

A recent study reported significant association of late-onset Alzheimer's disease (LOAD) with multiple single nucleotide polymorphisms (SNPs) and haplotypes in SORL1, a neuronal sortilin-related receptor protein known to be involved in the trafficking and processing of amyloid precursor protein. Here we attempted to validate this finding in three large, well characterized case-control series. Approximately 2000...

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Identifiers

PMID: 17949987
DOI: 10.1016/j.nbd.2007.09.001
PMCID: PMC2323581

Genes

SORL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.