Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of distinct variants in SORL1 with cerebrovascular and neurodegenerative changes related to Alzheimer disease.

Archives of neurology - 1 Dec 2008

T Cuenco Karen, Lunetta Kathryn L, Baldwin Clinton T, McKee Ann C, Guo Jianping, Cupples L Adrienne, Green Robert C, St George-Hyslop Peter H, Chui Helena, DeCarli Charles, Farrer Lindsay A

Abstract excerpt

BACKGROUND: Single-nucleotide polymorphisms (SNPs) in 2 distinct regions of the gene for the sortilin-related receptor (SORL1) (bounded by consecutively numbered SNPs 8-10 and 22-25) were shown to be associated with Alzheimer disease (AD) in multiple ethnically diverse samples. OBJECTIVE: To test...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Cerebrovascular Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to LDL-Receptor Related Proteins

Share to Magnetic Resonance Imaging

Share to Membrane Transport Proteins

Share to Models, Biological

Share to Nerve Degeneration

Share to Neuropsychological Tests

Source

Open in PubMed Open full text

Identifiers

PMID: 19064752
DOI: 10.1001/archneur.65.12.1640
PMCID: PMC2719762

Genes

SORL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19064752-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of distinct variants in SORL1 with cerebrovascular and neurodegenerative changes related to Alzheimer disease.PMID 19064752Read ↗

Association of SORL1 gene variants with hippocampal and cerebral atrophy and Alzheimer's disease.Semantic proximity Read ↗

Meta-analysis of the association between variants in SORL1 and Alzheimer disease.Semantic proximity Read ↗

Association of the Alzheimer's gene SORL1 with hippocampal volume in young, healthy adults.Semantic proximity Read ↗

The SORL1 gene and convergent neural risk for Alzheimer's disease across the human lifespan.Semantic proximity Read ↗

Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brainSemantic proximity Read ↗

Impact of SORL1 genetic variations on MRI markers in non-demented elders.Semantic proximity Read ↗

Impact of SORL1 single nucleotide polymorphisms on Alzheimer's disease cerebrospinal fluid markers.Semantic proximity Read ↗

SORL1 variants and risk of late-onset Alzheimer's disease.Semantic proximity Read ↗

SORL1 mutations in early- and late-onset Alzheimer diseaseSemantic proximity Read ↗

Heterozygous and Homozygous Variants in SORL1 Gene in Alzheimer's Disease Patients: Clinical, Neuroimaging and Neuropathological Findings.Semantic proximity Read ↗

The neuronal sortilin-related receptor gene SORL1 and late-onset Alzheimer's disease.Semantic proximity Read ↗

Sequence variation in SORL1 and dementia risk in Swedes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.