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Article

Association of the Alzheimer's gene SORL1 with hippocampal volume in young, healthy adults.

The American journal of psychiatry - 1 Oct 2011

Bralten Janita, Arias-Vásquez Alejandro, Makkinje Remco, Veltman Joris A, Brunner Han G, Fernández Guillén, Rijpkema Mark, Franke Barbara

Abstract excerpt

OBJECTIVE: Alzheimer's disease is among the most common neurodegenerative disorders. The SORL1 (sortilin receptor 1) gene is associated with the disease, but different variants seem to contribute. The authors used a gene-wide approach to test whether SORL1 is associated with volume of the hippocampus, one of the first structures to be affected by Alzheimer's disease in young, healthy individuals, in an attempt to...

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Source

Identifiers

PMID: 21730226
DOI: 10.1176/appi.ajp.2011.10101509

Genes

SORL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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