Article
Impact of SORL1 single nucleotide polymorphisms on Alzheimer's disease cerebrospinal fluid markers.
Dementia and geriatric cognitive disorders - 1 Jan 2011
Alexopoulos Panagiotis, Guo Liang-Hao, Kratzer Martina, Westerteicher Christine, Kurz Alexander, Perneczky Robert
Abstract excerpt
BACKGROUND: Recently, genetic variants of the neuronal sortilin-related receptor with A-type repeats (SORL1, also called LR11 or sorLA) have emerged as risk factors for the development of Alzheimer's disease (AD). METHODS: In this study, SORL1 gene polymorphisms, which have been shown to be related to AD, were analyzed for associations with cerebrospinal fluid (CSF) amyloid beta1-42 (Aβ(1-42)), phosphorylated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
