Impact of SORL1 single nucleotide polymorphisms on Alzheimer's disease cerebrospinal fluid markers.

doi:10.1159/000332017

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Article

Impact of SORL1 single nucleotide polymorphisms on Alzheimer's disease cerebrospinal fluid markers.

Dementia and geriatric cognitive disorders - 1 Jan 2011

Alexopoulos Panagiotis, Guo Liang-Hao, Kratzer Martina, Westerteicher Christine, Kurz Alexander, Perneczky Robert

Abstract excerpt

BACKGROUND: Recently, genetic variants of the neuronal sortilin-related receptor with A-type repeats (SORL1, also called LR11 or sorLA) have emerged as risk factors for the development of Alzheimer's disease (AD). METHODS: In this study, SORL1 gene polymorphisms, which have been shown to be related to AD, were analyzed for associations with cerebrospinal fluid (CSF) amyloid beta1-42 (Aβ(1-42)), phosphorylated...

Topics

Aged
Aged, 80 and over
Alzheimer Disease
Amyloid beta-Peptides
Apolipoproteins E
Biomarkers
DNA
Data Interpretation, Statistical
Databases, Factual
Female
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

LDL-Receptor Related Proteins

Male

Membrane Transport Proteins

Middle Aged

Peptide Fragments

Polymorphism, Single Nucleotide

Regression Analysis

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Open in PubMed Open full text

Identifiers

PMID: 21997402
DOI: 10.1159/000332017
PMCID: PMC3696367

Genes

SORL1
APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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