Article
Relationship between ST8SIA2, polysialic acid and its binding molecules, and psychiatric disorders.
Biochimica et biophysica acta - 1 Aug 2016
Sato Chihiro, Hane Masaya, Kitajima Ken
Abstract excerpt
Polysialic acid (polySia, PSA) is a unique and functionally important glycan, particularly in vertebrate brains. It is involved in higher brain functions such as learning, memory, and social behaviors. Recently, an association between several genetic variations and single nucleotide polymorphisms (SNPs) of ST8SIA2/STX, one of two polysialyltransferase genes in vertebrates, and psychiatric disorders, such as...
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