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Article

Schizophrenia-like phenotype of polysialyltransferase ST8SIA2-deficient mice.

Brain structure & function - 1 Jan 2015

Kröcher Tim, Malinovskaja Kristina, Jürgenson Monika, Aonurm-Helm Anu, Zharkovskaya Tamara, Kalda Anti, Röckle Iris, Schiff Miriam, Weinhold Birgit, Gerardy-Schahn Rita, Hildebrandt Herbert, Zharkovsky Alexander

Abstract excerpt

Posttranslational modification of the neural cell adhesion molecule (NCAM) by polysialic acid (polySia) is crucial for nervous system development and brain plasticity. PolySia attachment is catalyzed by the polysialyltransferases (polySTs) ST8SIA2 and ST8SIA4, two enzymes with distinct but also common functions during neurodevelopment and in the adult brain. A growing body of evidence links aberrant levels of...

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PMID: 24057454
DOI: 10.1007/s00429-013-0638-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Schizophrenia-like phenotype of polysialyltransferase ST8SIA2-deficient mice.PMID 24057454Read ↗

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