Article
Different properties of polysialic acids synthesized by the polysialyltransferases ST8SIA2 and ST8SIA4.
Glycobiology - 1 Sept 2017
Mori Airi, Hane Masaya, Niimi Yuki, Kitajima Ken, Sato Chihiro
Abstract excerpt
Polysialic acid (polySia) is mainly found as a modification of neural cell adhesion molecule (NCAM) in whole embryonic brains, as well as restricted areas of adult vertebrate brains, including the hippocampus. PolySia shows not only repulsive effects on NCAM-involved cell-cell interactions due to its bulky and hydrated properties, but also attractive effects on the interaction with neurologically active...
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