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Article

Sialyltransferase ST8Sia-II assembles a subset of polysialic acid that directs hippocampal axonal targeting and promotes fear behavior.

The Journal of biological chemistry - 30 Jul 2004

Angata Kiyohiko, Long Jeffrey M, Bukalo Olena, Lee Wenjau, Dityatev Alexander, Wynshaw-Boris Anthony, Schachner Melitta, Fukuda Minoru, Marth Jamey D

Abstract excerpt

Polysialic acid (PSA) is a post-translational protein modification that is widely expressed among neural cell types during development. Found predominantly on the neural cell adhesion molecule (NCAM), PSA becomes restricted to regions of neurogenesis and neuroplasticity in the adult. In the mammalian genome, two polysialyltransferases termed ST8Sia-II and ST8Sia-IV have been hypothesized to be responsible for the...

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PMID: 15140899
DOI: 10.1074/jbc.M403429200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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