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Impact of structural aberrancy of polysialic acid and its synthetic enzyme ST8SIA2 in schizophrenia

1 Jan 2013

Abstract excerpt

Psychiatric disorders are a group of human diseases that impair higher cognitive functions. Whole-genomic analyses have recently identified susceptibility genes for several psychiatric disorders, including schizophrenia. Among the genes reported to be involved in psychiatric disorders, a gene encoding a polysialyltransferase involved in the biosynthesis of polysialic acid (polySia or PSA) on cell surfaces has...

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PMID: 23675315
DOI: 10.3389/fncel.2013.00061

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