Article

ST8Sia2 polysialyltransferase protects against infection by <i>Trypanosoma cruzi</i>

2023-11-14

Abstract excerpt

<h4>ABSTRACT</h4> Glycosylation is one of the most structurally and functionally diverse co- and post-translational modifications in a cell. Addition and removal of glycans, especially to proteins and lipids, characterize this process which have important implications in several biological processes. In mammals, the repeated enzymatic addition of a sialic acid unit to underlying sialic acids (Sia) by polysialyltr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7978fe62-acc6-5601-8156-e0e234c953d6
DOI: 10.1101/2023.11.14.567071

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

ST8Sia2 polysialyltransferase protects against infection by <i>Trypanosoma cruzi</i>DOI 10.1101/2023.11.14.567071Read

Sialic acid: a sweet swing between mammalian host and Trypanosoma cruziSemantic proximity Read

Role of Trypanosoma cruzi Trans-sialidase on the Escape from Host Immune SurveillanceSemantic proximity Read

Genomic Analyses, Gene Expression and Antigenic Profile of the Trans-Sialidase Superfamily of Trypanosoma cruzi Reveal an Undetected Level of ComplexitySemantic proximity Read

Deletion of the glucosidase II gene in Trypanosoma brucei reveals novel N-glycosylation mechanisms in the biosynthesis of variant surface glycoprotein.Semantic proximity Read

Evolution of sialic acids: Implications in xenotransplant biologySemantic proximity Read

Enabling tools for <i>Toxoplasma</i> glycobiologySemantic proximity Read

Protein <i>N</i> -glycosylation is essential for SARS-CoV-2 infectionSemantic proximity Read

Hyposialylation Must Be Considered to Develop Future Therapies in Autoimmune DiseasesSemantic proximity Read

Automated N-glycan profiling of a mutant Trypanosoma rangeli sialidase expressed in Pichia pastoris, using tandem mass spectrometry and bioinformatics.Semantic proximity Read

Disruption of Active Trans-Sialidase Genes Impairs Egress from Mammalian Host Cells and Generates Highly Attenuated Trypanosoma cruzi ParasitesSemantic proximity Read

Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation.Semantic proximity Read

Generation of constitutive and inducible trans-sialylation dominant-negative phenotypes in Trypanosoma brucei and Trypanosoma cruzi.Semantic proximity Read