Biallelic editing of a lamprey genome using the CRISPR/Cas9 system.

doi:10.1038/srep23496

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Biallelic editing of a lamprey genome using the CRISPR/Cas9 system.

Scientific reports - 23 Mar 2016

Zu Yao, Zhang Xushuai, Ren Jianfeng, Dong Xuehong, Zhu Zhe, Jia Liang, Zhang Qinghua, Li Weiming

Abstract excerpt

Lampreys are extant representatives of agnathans. Descriptions of lamprey development, physiology and genome have provided critical insights into early evolution of vertebrate traits. However, efficient means for genetic manipulation in agnathan species have not been developed, hindering functional studies of genes in these important Evo-Devo models. Here, we report a CRISPR/Cas system optimized for lamprey...

Topics

Alleles
Animals
CRISPR-Cas Systems
Genetic Engineering
Genome
INDEL Mutation
Lampreys
Mutation Rate
Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 27005311
DOI: 10.1038/srep23496
PMCID: PMC4804306

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics