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Efficient CRISPR genome editing and integrative genomic analyses reveal the mosaicism of Cas-induced mutations and pleiotropic effects of <i>scarlet</i> gene in an emerging model system

2024-01-31

Abstract excerpt

Despite the revolutionary impacts of CRISPR-Cas gene editing systems, the effective and widespread use of CRISPR technologies in emerging model organisms still faces significant challenges. These include the inefficiency in generating heritable mutations at the organismal level, limited knowledge about the genomic consequences of gene editing, and an inadequate understanding of the inheritance patterns of CRISPR-C...

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Literature Corpus work
17f30c02-3ce1-5db4-8ecf-3737ea5a89f7
DOI
10.1101/2024.01.29.577787
Open publication

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Efficient CRISPR genome editing and integrative genomic analyses reveal the mosaicism of Cas-induced mutations and pleiotropic effects of <i>scarlet</i> gene in an emerging model systemDOI 10.1101/2024.01.29.577787
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