Article
Targeted Mutagenesis in Zebrafish Using CRISPR RNA-Guided Nucleases.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015
Hwang Woong Y, Fu Yanfang, Reyon Deepak, Gonzales Andrew P W, Joung J Keith, Yeh Jing-Ruey Joanna
Abstract excerpt
In recent years, the zebrafish has become a critical contributor to various areas of biomedical research, advancing our fundamental understanding of biomedicine and helping discover candidate therapeutics for human diseases. Nevertheless, to further extend the power of this important model organism requires a robust and simple-to-use genome editing platform that will enable targeted gene knockouts and...
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