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Article

CRISPR/Cas9-mediated mutagenesis in the sea lamprey Petromyzon marinus: a powerful tool for understanding ancestral gene functions in vertebrates.

Development (Cambridge, England) - 1 Dec 2015

Square Tyler, Romášek Marek, Jandzik David, Cattell Maria V, Klymkowsky Michael, Medeiros Daniel M

Abstract excerpt

Lamprey is one of only two living jawless vertebrates, a group that includes the first vertebrates. Comparisons between lamprey and jawed vertebrates have yielded important insights into the origin and evolution of vertebrate physiology, morphology and development. Despite its key phylogenetic position, studies of lamprey have been limited by their complex life history, which makes traditional genetic approaches...

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Identifiers

PMID: 26511928
DOI: 10.1242/dev.125609
PMCID: PMC4712834

Genes

FGF8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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